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Sponsor and investor information packet: B. Cepacia and Biofilm
Biofilm, formed of a complex matrix of polysaccharides, can shield bacteria from antibiotic treatments. In fact, the presence of biofilm renders antibiotics 1000 to 10,000 times less effective than they would be without the presence of biofilm. According to the Townsend Letter for Doctors and Patients, “Their anti-microbial resistance coupled with the inaccuracy of current lab tests to diagnose hidden biofilms and intracellular infections makes biofilms the greatest clinical challenge facing doctors today. This dynamic with biofilms is especially important to patients with Cystic fibrosis and pseudomonas aeruginosa and B. Cepacia.”
Currently we are performing manual computer based literature research, phone interviews and automated machine based mining of the world’s literature on these subjects. We have developed collaborative relationships with other researchers including physicians and scientists at the Center for Biofilm Engineering at Montana State University, Binghamton University in NY.
Other related organizations are the Technical University of Denmark (DTU), and the Cystic Fibrosis Foundation.
Extending from the initial research, Rational Data is also researching biofilm dispersion techniques in order to identify methods of breaking down biofilm. This involves literature searches and biochemical research involving polysaccharides.
This research has the potential to affect at least two fields. The first is its potential to improve the treatment of serious medical conditions, including infections in people with cystic fibrosis that are eventually fatal. Second, such research could affect industrial applications, such as preventing corrosion in pipes by biofilms, and preventing bacterial inhabitation of machinery in food processing plants.
Rational Data is currently constructing data sets and building the Biofilm collaborative space. When complete, we will invite those in the field to participate in this space and to subscribe to this area of cyberspace. Fees from these services will support income streams paid to online real estate and digital property investors.
